Objective: To evaluate the effects of low-dosage (3 μg/kg/min) dopamine on urine output, renal blood flow, creatinine clearance, sodium excretion, heart rate, and mean arterial pressure (MAP) in healthy anesthetized cats.
Design: Controlled experimental study.
Setting: University experimental laboratory.
Animals: Twelve random-bred 2–4-year-old cats.
Interventions: Anesthesia, laparotomy for renal artery blood flow measurement, and arterial and venous catheterization.
Main results: No significant difference in urine output, sodium excretion, HR, or creatinine clearance occurred in cats receiving low-dosage dopamine. A transient decrease in the mean arterial blood pressure occurred in cats receiving dopamine.
Conclusions: Low-dosage dopamine cannot be expected to induce diuresis in healthy cats. Low-dosage dopamine may cause vasodilation in non-renal vascular beds.